
Does Our Metabolism Really Slow Down?
Many people believe that after the age of 30 or 40, their metabolism slows down, making it easier to gain weight. But the truth is our metabolism remains relatively stable until around the age of 60! So why do we tend to gain weight as we get older? This article will take a deep dive into the facts that Andrew Huberman has shared about metabolism and aging.
1. Metabolism Does Not Slow Down in Your 30s or 40s
There is a widespread misconception that after turning 30, our metabolism starts to decline, leading to weight gain. However, research has found that metabolism remains stable until around age 60. This means that weight gain is not necessarily due to a slowing metabolism but rather changes in lifestyle.


2. Why Do We Gain Weight as We Age?
Even though metabolism does not change significantly in early adulthood, many aspects of our lives do, making weight gain more likely. Here are some key factors:
- A More Sedentary Lifestyle – As careers progress, many people spend more time sitting at desks and moving less throughout the day, leading to reduced calorie expenditure.
- Changes in Diet – As people become more financially stable, they often consume higher-calorie foods, including fatty foods, fast food, and sugary drinks.
- Loss of Muscle Mass – Muscle is the most metabolically active tissue in the body. If we exercise less or fail to maintain muscle as we age, our resting metabolic rate naturally decreases.
Studies indicate that between the ages of 20 and 50, the average person gains about 15 kg (32 lbs), or roughly 1-2 kg per year. This weight gain is the result of cumulative lifestyle choices, not a metabolic decline!
3. After Age 60, Metabolism Does Start to Decline
Although metabolism remains stable before age 60, it does start to slow down slightly after this point.
One of the most noticeable changes is the accumulation of “middle-age belly fat”, which occurs due to a combination of reduced calorie burn and decreased physical activity.
4. How to Prevent Weight Gain as You Age
- Build and Maintain Muscle Mass – Muscle is key to sustaining a high metabolism. Strength training, such as weightlifting or bodyweight exercises, helps preserve muscle mass and prevent metabolic decline.
- Increase Daily Movement – Avoid prolonged sitting and try to move frequently throughout the day, whether it’s taking the stairs instead of the elevator or incorporating short walks into your routine.
- Choose Healthier Foods – Reduce intake of high-calorie, low-nutrient foods such as sugar and fried foods. Instead, prioritize protein, fiber, and healthy fats.
- Control Portion Sizes – As we age, our energy needs slightly decrease, so it’s important to adjust food intake accordingly and avoid overeating.
- Stay Hydrated – Sometimes the body signals hunger when it is actually dehydrated, so drinking enough water throughout the day can help control unnecessary cravings.
5. Can PCB-154 Peptide Help?
There has been some confusion around PCB-154, but the peptide that has received the most attention is BPC-157, which has been studied for its potential tissue healing and anti-inflammatory properties.
BPC-157 has shown promise in promoting muscle, tendon, and digestive system healing, but human clinical studies are still lacking.
There are concerns that BPC-157 may promote tumor growth since it plays a role in angiogenesis (the formation of new blood vessels).
BPC-157 is not approved for human use by major regulatory bodies like the FDA and is banned by anti-doping organizations such as WADA.
While BPC-157 may have potential benefits in tissue repair, it also carries significant risks. It is crucial to consult with a healthcare professional before considering its use, especially since it has not been officially approved for human consumption.
6. Conclusion: Metabolism Is Not the Main Factor Behind Weight Gain!
Metabolism remains stable until around age 60. Weight gain before then is primarily due to lifestyle factors, not metabolic slowdown.
After age 60, metabolism does start to decline, but its effects can be managed by maintaining muscle mass and staying physically active.
BPC-157 may have potential in tissue repair but lacks sufficient human studies and poses possible risks.
If you want to maintain good health and control your weight effectively, start building muscle, staying active, and making better food choices today!